Leukoplakia

What is Leukoplakia?

The term Leukoplakia doesnt describe a specific disease but a clinical observation. Clinically Leukoplakia looks like a white patch which cannot be removed. It can have different surfaces such as smooth, fissured, varicous or speckled. Risk factors of Leukoplakia are the “6 s”

  • Smoking
  • Spirit
  • Sharp tooth( traumatic origin)
  • Spicy food
  • Syphilis
  • Sepsis (specifically candida infection and human papilloma virus).

Beside the etiological factors above a Vitamin A deficiency can cause a Leukoplakia as well.
Leukoplakia can be differentiated in 4 clinical stages based on its size an 5 stages based on its histopathological status which are:

  • No dysplasia
  • Mild dysplasia
  • Moderate dysplasia
  • Severe dysplasia(with high risk to be transformed to oral cancer)
  • Squamous cell carcinoma in situ with a poor prognosis and high letality

The surface of Leukoplakia can vary not only in its size but as well in its clinical appearance which could be :

-smooth
-fissured
-verruciform
-speckled

picture different surfaces

A biopsy would be needed in case a leukoplakia is detected as the following lesions look similar:

– White spongus nevus
– Lichen planus
– Acute pseudomembranous candida albicans
– Morsicatio buccarum
– Leukoedema

Leukoplakia can be treated by non surgical approach is:

  • Vitamin A
  • Vitamin E
  • Vitamin C
  • Or Others

Then the invasive approach could be performed by.

-Cryotherapy
-Carbon dioxide or Erbium Yag Laset therapy(Excision or Vaporization)
-Electrocautery
-Surgical excision

Always watch out for uncommon appearances in your mouth as they can be related to serious conditions like oral cancer or other systemic diseases.

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